Predicting learning and achievement using GABA and glutamate concentrations in human development

Previous research has highlighted the role of glutamate and gamma-aminobutyric acid (GABA) in learning plasticity. What is currently unknown how this knowledge translates to real-life complex cognitive abilities that emerge slowly link between these neurotransmitters human plasticity shaped by development. While some have suggested a generic GABA plasticity, others hypothesized their involvement shapes sensitive periods during Here we used cross-sectional longitudinal design with 255 individuals (spanning primary school university) show intraparietal sulcus explain unique variance both current future mathematical achievement (approximately 1.5 years). Furthermore, our findings reveal dynamic dissociable predicting learning, which reversed development, therefore provide novel implications for models childhood adulthood.